It starts innocently. One day you find yourself replacing Apple Maps with Google Maps when it becomes available. Or maybe you fall in love with a new email application. You find, after not really using the default calendar app that there are more robust options out there.Source: http://feedproxy.google.com/~r/Techcrunch/~3/zqDj6667B6I/
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Princeton University evacuated its campus Tuesday morning in response to a bomb threat to "multiple unspecified" buildings, the school announced in an emergency bulletin.
All employees were directed to leave university offices at the Princeton, N.J., campus and were told, "Do not return to campus for any reason."
Bomb threat on campus. Pls evacuate campus and offices and go home. Updates to follow. Check email. NOT A TEST.
According to a tweet from the university, those without a vehicle to leave campus are being directed to an evacuation site by Princeton police.
Princeton said just after noon that it does not expect employees to return to work on Tuesday as it investigates the bomb threat.
"The University's Department of Public Safety is investigating the threat with local, state and federal law enforcement agencies," an update on the website said.
The spring semester has already concluded and commencement was held last week. Princeton spokesman Dan Day told WNBC there are some summer programs on campus.
The FBI is not participating at this time in the Princeton investigation, a representative told The Huffington Post, but cautioned "that can change at anytime."
Students who need a place to go are being directed to the Nassau Inn, Princeton Public Library and Princeton Arts Council building downtown.
A university update on Tuesday afternoon announced that authorities are currently inspecting buildings on Princeton's campus using bomb-sniffing dogs, and the search of campus facilities is expected to take several hours.
A bomb threat was also made on Tuesday near the Georgia State Capitol in Atlanta, USA Today reports.
This is a developing story, check back for updates.
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Source: http://www.huffingtonpost.com/2013/06/11/princeton-bomb-threat_n_3421603.html
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![[ Back to EurekAlert! ]](http://www.eurekalert.org/images/back2e.gif){kind=small}
Public release date: 10-Jun-2013
Share ] Contact: Dr. Thomas Efferth
efferth@uni-mainz.de
49-613-139-25751
Johannes Gutenberg Universitaet Mainz
African medicinal plants contain chemicals that may be able to stop the spread of cancer cells. This is the conclusion of researchers following laboratory experiments conducted at Johannes Gutenberg University Mainz (JGU). The plant materials will now undergo further analysis in order to evaluate their therapeutic potential. "The active substances present in African medicinal plants may be capable of killing off tumor cells that are resistant to more than one drug. They thus represent an excellent starting point for the development of new therapeutic treatments for cancers that do not respond to conventional chemotherapy regimens," explained Professor Thomas Efferth of the Institute of Pharmaceutical Sciences and Biochemistry Therapeutic Life Sciences at Mainz University. For the past four years, Efferth and biochemist Dr. Victor Keute of the University of Dschang in Cameroon have been studying the active substances in African plants such as the giant globe thistle, wild pepper, speargrass, and Ethiopian pepper.
Multi-drug resistance is one of the most feared problems in cancer therapy because in such cases most of the standard chemical cancer drugs used in therapy fail and the patient's chance of survival is thus dramatically reduced. The problem cannot usually be resolved by simply increasing the dosage as this also results in the exacerbation of undesirable side effects. "We are now looking for substances that can both break down tumor resistance and not produce side effects," continued Efferth, who also works with medicinal plants used in traditional Chinese medicine.
Many plants contain toxic substances that they use to protect themselves against predators and microbial diseases. Over the course of millions of years during which life has evolved on earth plants have managed to appropriate certain molecules to help them to offset their main disadvantage in the face of their enemies, i.e., their immobility and lack of an immune system. The challenge for the pharmacologists is now to determine which plant substances are medicinal and which are simply poisonous and dangerous.
During the joint project with Mainz, the Cameroonian scientist Victor Kuete has examined more than 100 spices and plants from his homeland for their cytotoxic effects on cancer cells. Awarded a Humboldt Research Fellowship, he can now continue and extend his investigations as a member of Thomas Efferth's work group in Mainz. "We have already found an entire series of benzophenones and other phytochemicals that are able to elude resistance mechanisms and thus offer many new opportunities for continued research," said Efferth.
The researchers are focusing on three different resistance mechanisms. Transporter-mediated resistance prevents drugs taking effect because a substance called P-glycoprotein promotes their efflux from cancer cells. In the case of tumor-suppressor-gene-mediated resistance, a mutation in protein p53 means that the cancer cells do not die but are resistant and become increasingly aggressive. Lastly, in oncogene-mediated resistance, the epidermal growth factor receptor (EGFR) sends signals into the interior of cells causing tumors to grow faster. The researchers in Mainz have cellular models of all three resistance mechanisms that will enable them to appropriately test the effectiveness of the substances obtained from plants.
In their latest of a total of eight publications produced to date, the research team reports that four naturally occurring benzophenones can prevent the proliferation of the tested cancer cell lines, including multi-drug resistant strains. "The benzophenones investigated are potentially cytotoxic substances that need to be more extensively investigated with the aim of developing new cancer drugs that are effective against susceptible and resistant cancers", claims the article recently published in the scientific journal Phytomedicine.
###
Images:
http://www.uni-mainz.de/bilder_presse/09_pharma_heilpflanzen_piper_capensis.jpg
Wild pepper seeds
photo: Victor Kuete, Institute of Pharmaceutical Sciences and Biochemistry Therapeutic Life Sciences
http://www.uni-mainz.de/bilder_presse/09_pharma_heilpflanzen_echinops_giganteus.jpg
Sections of the root of the giant globe thistle
photo: Victor Kuete, Institute of Pharmaceutical Sciences and Biochemistry Therapeutic Life Sciences
Publications:
Victor Kuete et al.
Cytotoxicity and modes of action of four naturally occuring benzophenones: 2,2_,5,6_-Tetrahydroxybenzophenone,
guttiferone E, isogarcinol and isoxanthochymol
Phytomedicine, April 2013
DOI: 10.1016/j.phymed.2013.02.003
Victor Kuete et al.
Anticancer Activities of Six Selected Natural Compounds of Some Cameroonian Medicinal Plants
PLoS ONE, August 2011
DOI:10.1371/journal.pone.0021762
[ | E-mail | Share ] ?
AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert! system.
Public release date: 10-Jun-2013 Share ] Contact: Dr. Thomas Efferth
efferth@uni-mainz.de
49-613-139-25751
Johannes Gutenberg Universitaet Mainz
African medicinal plants contain chemicals that may be able to stop the spread of cancer cells. This is the conclusion of researchers following laboratory experiments conducted at Johannes Gutenberg University Mainz (JGU). The plant materials will now undergo further analysis in order to evaluate their therapeutic potential. "The active substances present in African medicinal plants may be capable of killing off tumor cells that are resistant to more than one drug. They thus represent an excellent starting point for the development of new therapeutic treatments for cancers that do not respond to conventional chemotherapy regimens," explained Professor Thomas Efferth of the Institute of Pharmaceutical Sciences and Biochemistry Therapeutic Life Sciences at Mainz University. For the past four years, Efferth and biochemist Dr. Victor Keute of the University of Dschang in Cameroon have been studying the active substances in African plants such as the giant globe thistle, wild pepper, speargrass, and Ethiopian pepper.
Multi-drug resistance is one of the most feared problems in cancer therapy because in such cases most of the standard chemical cancer drugs used in therapy fail and the patient's chance of survival is thus dramatically reduced. The problem cannot usually be resolved by simply increasing the dosage as this also results in the exacerbation of undesirable side effects. "We are now looking for substances that can both break down tumor resistance and not produce side effects," continued Efferth, who also works with medicinal plants used in traditional Chinese medicine.
Many plants contain toxic substances that they use to protect themselves against predators and microbial diseases. Over the course of millions of years during which life has evolved on earth plants have managed to appropriate certain molecules to help them to offset their main disadvantage in the face of their enemies, i.e., their immobility and lack of an immune system. The challenge for the pharmacologists is now to determine which plant substances are medicinal and which are simply poisonous and dangerous.
During the joint project with Mainz, the Cameroonian scientist Victor Kuete has examined more than 100 spices and plants from his homeland for their cytotoxic effects on cancer cells. Awarded a Humboldt Research Fellowship, he can now continue and extend his investigations as a member of Thomas Efferth's work group in Mainz. "We have already found an entire series of benzophenones and other phytochemicals that are able to elude resistance mechanisms and thus offer many new opportunities for continued research," said Efferth.
The researchers are focusing on three different resistance mechanisms. Transporter-mediated resistance prevents drugs taking effect because a substance called P-glycoprotein promotes their efflux from cancer cells. In the case of tumor-suppressor-gene-mediated resistance, a mutation in protein p53 means that the cancer cells do not die but are resistant and become increasingly aggressive. Lastly, in oncogene-mediated resistance, the epidermal growth factor receptor (EGFR) sends signals into the interior of cells causing tumors to grow faster. The researchers in Mainz have cellular models of all three resistance mechanisms that will enable them to appropriately test the effectiveness of the substances obtained from plants.
In their latest of a total of eight publications produced to date, the research team reports that four naturally occurring benzophenones can prevent the proliferation of the tested cancer cell lines, including multi-drug resistant strains. "The benzophenones investigated are potentially cytotoxic substances that need to be more extensively investigated with the aim of developing new cancer drugs that are effective against susceptible and resistant cancers", claims the article recently published in the scientific journal Phytomedicine.
###
Images:
http://www.uni-mainz.de/bilder_presse/09_pharma_heilpflanzen_piper_capensis.jpg
Wild pepper seeds
photo: Victor Kuete, Institute of Pharmaceutical Sciences and Biochemistry Therapeutic Life Sciences
http://www.uni-mainz.de/bilder_presse/09_pharma_heilpflanzen_echinops_giganteus.jpg
Sections of the root of the giant globe thistle
photo: Victor Kuete, Institute of Pharmaceutical Sciences and Biochemistry Therapeutic Life Sciences
Publications:
Victor Kuete et al.
Cytotoxicity and modes of action of four naturally occuring benzophenones: 2,2_,5,6_-Tetrahydroxybenzophenone,
guttiferone E, isogarcinol and isoxanthochymol
Phytomedicine, April 2013
DOI: 10.1016/j.phymed.2013.02.003
Victor Kuete et al.
Anticancer Activities of Six Selected Natural Compounds of Some Cameroonian Medicinal Plants
PLoS ONE, August 2011
DOI:10.1371/journal.pone.0021762
[ | E-mail | Share ] ?
AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert! system.
Source: http://www.eurekalert.org/pub_releases/2013-06/jgum-sfa061013.php
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This week, CrunchBase released the?May Excel Export Sheet, which includes charts and graphs that illustrate recent U.S. investments, acquisitions, IPOs and more. Though the charts and graphs focus on May's data, the spreadsheet includes historical data on all U.S.-based companies that have received funding.Source: http://feedproxy.google.com/~r/Techcrunch/~3/-cWQql8M8kQ/
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June 10, 2013 ? Lone people standing in a ballroom don't tend to move a lot. It's only when they find a suitable dance partner that rapid motion sets in. Atoms on iron-oxide surfaces behave in a similar way: Only with the right molecular partner do they dance across the surface. Scientists at the Vienna University of Technology have now filmed the atoms, proving that carbon monoxide is the partner responsible for the quick motion. Their movies show that the motion leads directly to clustering -- an effect that can do great harm in catalysts.
The findings have now been published in the journal Nature Materials.
Clusters -- What a Waste of Atoms!
"Metals such as gold or palladium are often used as catalysts to speed up certain chemical reactions," says Professor Ulrike Diebold (Institute of Applied Physics, Vienna University of Technology). When the atoms ball together, most of them do not get into contact with the surrounding gas any more and the catalytic effect diminishes drastically. For this reason, Ulrike Diebold's team investigates how clusters form from single atoms on a surface, and search for ways to inhibit the process.
Theories about this effect have been discussed for years, but the researchers at the Vienna University of Technology have now directly observed the clustering of the atoms. "We are using palladium atoms on an extremely clean iron-oxide surfaces in an ultra high vacuum chamber. For several hours, we take pictures of the surface with a scanning tunneling microscope," says Gareth Parkinson (Vienna University of Technology). These pictures were then made into a movie, in which the paths of the individual atoms could be tracked.
The Skyhook Effect
Using this technique, the research team discovered that the rapid atomic dance on the surface is initiated by carbon monoxide molecules, which bind to individual palladium atoms. As soon as this happens, the palladium is hardly connected to the ground and can move around almost freely, as if it had been lifted out by the carbon monoxide. "This is known as the skyhook effect," says Zbynek Novotny (Vienna University of Technology).The carbon monoxide and palladium move happily together across the surface, until they collide with other 'dancing couples'. Then, they stick together creating a small cluster that continues to grow.
Hydroxyl Against Clustering?
With the new possibility of watching clustering in real-time under the microscope, the mechanisms can now be studied in detail: "We discovered that OH groups on the surface can suppress the clustering effect," says Gareth Parkinson. If the carbon monoxide-palladium couples do not encounter each other, but instead find an OH group, they get trapped there and cannot form a cluster. A hydroxyl coating of the surface could therefore lead to a significant improvement of the stability of catalysts.
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It’s fair to say that the “ambient location” craze has passed. Several of the mobile apps intent on connecting people with friends and other recommended users nearby are still struggling to find mainstream adoption. Some, like Glancee and Glassmap have sold. Others, like Kismet, have moved into new product categories. And today, the business-focused networking app Intro, is pivoting. Gone are the “ambient location” features which once alerted you to nearby users based on things like geotagged tweets or check-ins. With the new version, the company has shifted the focus solely to making one-to-one introductions between members of LinkedIn or Meetup groups. Explains co-founder?Anthony Erwin, the decision to make this switch came from observations of user behavior. The best and most powerful introductions the app enabled were those where the members were each in the same group already. 90 percent of the time when an intro was created and members would connect, they cited being in the same group as the reason, he says. “I think what’s happened in this space, is because it’s dealing with connecting strangers – people are kind of wary of that,” says Erwin. “If you’re going to create connections that work, they’re going to have to be very familiar; almost not like strangers, in a way.” Users told him that when they were shown other group members, those people didn’t feel like random strangers. Intro has always been more sensitive to the potentially creepy nature of ambient location apps, having previously introduced features that would allow users to switch of networking with those not outside of a set of preferred groups, for instance. The revamped version of the app is something of an extension of that earlier concept more than it is a hard pivot to an entirely new vertical. In the updated application, available now on iOS and for Android in a few weeks time (currently the Android app is the older version of Intro), you’ll still be shown other group members who are nearby, but now the app take a wider view of your location. It begins by offering you connections across your city, as opposed to at your exact location. You can then quickly swipe through the suggestions to connect or reject the proposed connections. However, when there is an event or other congregation of members in the same location, the app’s algorithm will immediately adjust to sort its recommendations by degreesSource: http://feedproxy.google.com/~r/Techcrunch/~3/mFt0KUibQtg/
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NEW YORK (AP) ? Even on the unemployment line, Tim Tebow remains a popular presence.
The former Jets quarterback, cut by New York last week after one disappointing season and now a free agent, was selected as America's most influential athlete, according to a survey released Monday by Forbes.com.
Tebow had the most influence on fans, according to 29 percent of respondents, finishing ahead of Olympic swimmer Michael Phelps (25 percent), Jamaican track star Usain Bolt (23 percent) and Yankees shortstop Derek Jeter (22 percent).
Forbes.com used surveys from Nielsen and E-Poll Market Research to determine the winner, and took into account Nielsen's measurement for a player's endorsement potential.
The next-closest NFL player was Denver's Peyton Manning, who replaced Tebow with the Broncos last offseason and finished fifth in the survey.
Source: http://news.yahoo.com/forbes-poll-tabs-tebow-most-influential-athlete-224055703.html
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BEIRUT (AP) ? Israeli warplanes struck targets in the Syrian capital Sunday for the second time in three days, officials and activists said, unleashing a series of massive explosions and raising fears of possible wider conflict in the region.
The attacks, which Israeli officials said targeted sophisticated, Iranian-made guided missiles believed to be bound for Lebanon's Hezbollah militant group, marked a sharp spike in Israel's involvement in Syria's bloody civil war. Syrian state media reported that Israeli missiles struck a military and scientific research center near Damascus and caused casualties.
Syria's government called the attacks against its territory a "flagrant violation of international law" that has made the Middle East "more dangerous." It said "Israel should know that our people and state do not accept humiliation" and warned Syria has the right "to defend its people by all available means."
The generally muted response, read out by the information minister after an emergency government meeting, and appeared to signal that Damascus did not want the situation to escalate.
Instead, it tried to use the strikes to taint the opposition, claiming the attacks were evidence of an alliance between Israel and Islamic extremist groups trying to overthrow President Bashar Assad.
The air raids pose a dilemma for the regime: Failure to respond could make it look weak and open the door to more strikes, but retaliating militarily against Israel would risk dragging the Jewish state and its powerful army into a broader conflict.
The tempo of the new strikes added a dangerous dynamic to the conflict, fueling concerns that events could spin out of control and spark a regional crisis.
Israel's military, possibly bracing for Syrian retaliation, deployed two batteries of its Iron Dome rocket defense system to the north of the country on Sunday. It described the move as part of "ongoing situational assessments."
A senior Israeli official, who spoke on condition of anonymity in order to disclose information about a secret military operation, confirmed that Israel launched an airstrike in the Syrian capital early Sunday but did not give more precise details about the location. The target was Fateh-110 missiles, which have precision guidance systems with better aim than anything Hezbollah is known to have in its arsenal, the official told The Associated Press.
The airstrikes come as Washington considers how to respond to indications that the Syrian regime may have used chemical weapons in its civil war. President Barack Obama has described the use of such weapons as a "red line," and the administration is weighing its options ? including possible military action.
The White House declined for a second day to confirm or comment directly on the airstrikes in Syria, but said Obama believes Israel has the right to defend itself against threats from groups like Hezbollah.
"The Israelis are justifiably concerned about the threat posed by Hezbollah obtaining advanced weapons systems, including some long-range missiles" White House spokesman Josh Earnest told reporters aboard Air Force One as Obama traveled to Ohio.
Iran, a close ally of the Assad regime and Hezbollah, condemned the airstrikes, and a senior official hinted at a possible response not from Tehran but rather its proxy, Hezbollah.
Gen. Masoud Jazayeri, assistant to the Iranian chief-of-staff, told Iran's state-run Arabic-language Al-Alam TV that Tehran "will not allow the enemy (Israel) to harm the security of the region" and that "the resistance will retaliate against the Israeli aggression against Syria."
Israel has said it wants to stay out of the Syrian war on its doorstep, but Prime Minister Benjamin Netanyahu has repeatedly stated the Jewish state would be prepared to take military action to prevent sophisticated weapons from flowing from Syria to Hezbollah or other extremist groups.
Israel and Hezbollah have a long history of enmity, and fought a punishing monthlong war in mid-2006. The militant group fired thousands of rockets at Israel, while Israeli warplanes destroyed large areas of southern and eastern Lebanon during a conflict that ended in stalemate.
With Syria now engulfed in an internal conflict, Israel is especially concerned that Hezbollah will take advantage of the chaos and try to smuggle advanced weapons into Lebanon, particularly those that could hamper Israel's ability to operate in Lebanese skies.
Officials in Israel say they have identified several "game changing" weapons that would trigger military intervention in Syria: chemical weapons, long-range Scud B missiles, the Fateh-110s, land-to-sea Yakhont missiles and SA-17 anti-aircraft missiles.
Israeli officials believe that Iran and Hezbollah are stepping up their efforts to smuggle weapons because they think Assad's days are numbered. They also think the Syrian leader is cooperating because he is weak and he owes Hezbollah, which is understood to be sending men to fight alongside government troops, for its support.
The officials, who spoke on condition of anonymity because they were not authorized to brief the media, said Israel will continue to strike Syria if the smuggling attempts continue.
An amateur video said to be shot early Sunday in the Damascus area showed a massive explosion followed by fire lighting up the night sky. The video appeared genuine and corresponded to other AP reporting.
The state news agency said the Jamraya military and scientific research center near Damascus was hit. It added that there were casualties but did not give a number.
Damascus-based activist Maath al-Shami said the strikes occurred around 3 a.m. and that one of them hit near Qasioun mountain that overlooks Damascus. He added that the raid targeted a military position for the elite Republican Guards unit that is in charge of protecting the capital.
Mohammed Saeed, another activist who lives in the Damascus suburb of Douma, said "the explosions were so strong that earth shook under us." He said the smell of the fire caused by the air raid near Qasioun was noticeable kilometers (miles) away.
In Jerusalem, Israeli media reported that Netanyahu held an emergency meeting of his inner Security Cabinet. The prime minister's office declined comment.
The strikes are a calculated risk for Israel. Officials there say they do not think Assad will retaliate in the immediate future, but they hedged their bets with the deployment of Iron Dome batteries to Israel's north.
Earlier this year, the Iron Dome system was credited with shooting down hundreds of rockets during a round of fighting against Hamas militants in the Gaza Strip.
Amos Yadlin, a former head of Israel's military intelligence, said the strikes on Syria are a signal to Damascus' ally, Tehran, that Israel is serious about the red lines it has set.
"Syria is a very important part in the front that Iran has built. Iran is testing Israel and the U.S. determination in the facing of red lines and what it sees is in clarifies to it that at least some of the players, when they define red lines and they are crossed, take it seriously," he told Army Radio.
Like the Syrian regime, Iran also portrayed the strike as evidence of collusion between Israel and Syria's rebels.
Iranian Defense Minister Gen. Ahmad Vahidi was quoted by the official IRNA news agency as saying the attacks show a growing alliance of convenience between the Syrian opposition and Israel.
"These vain moves are not a sign of Israel's power," he said. "It rather shows the (Israeli) regime's despair in the face of regional developments."
Iran has provided both financial and military support to Hezbollah for decades, and has used Syria as a conduit for both. If Assad were to fall, that pipeline could be cut, dealing a serious blow to Hezbollah's ability to confront Israel.
The Fateh-110, or "Conqueror" in Farsi, is a short-range ballistic missile developed by Iran and first put into service in 2002. The Islamic Republic unveiled an upgraded version in 2012 that improved the weapon's accuracy and increased its range to 300 kilometers (185 miles).
Vahidi said at the time that the solid-fueled missile could strike with pinpoint precision, making it the most accurate weapon of its kind in Iran's arsenal.
Israeli officials say that Hezbollah managed to get an older version of Fateh-110s back in 2010, but the missiles that were destroyed in the recent airstrikes are an upgraded version. Israeli intelligence thinks Hezbollah has not succeeded in getting any of these game changing weapons since the Syrian civil war erupted, according to the officials.
An Israeli airstrike in January also targeted weapons apparently bound for Hezbollah, Israeli and U.S. officials have said.
Hezbollah's Al-Manar TV said the research center in Jamraya was not hit, but instead an army supply facility that produced food products for the military. It quoted unnamed Syrian security officials as saying that three sites including military barracks, arms depots and air defense center were targeted by the strike.
The station aired footage showing a heavily damaged building as well as what appeared to be a chicken farm with some chickens pecking around in debris scattered with dead birds.A road apparently next to the site was filled with debris, and shell casings were strewn on the ground.
Lebanon's Al-Mayadeen TV, which has several reporters around Syria, said one of the strikes targeted a military position in the village of Saboura, west of Damascus and about 10 kilometers (six miles) from the Lebanon border.
___
Deitch reported from Jerusalem. Associated Press writers Ryan Lucas in Beirut and Brian Murphy in Dubai, United Arab Emirates, contributed to this report.
Source: http://news.yahoo.com/tensions-spike-israeli-strikes-syria-151613082.html
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May 6, 2013 ? A team led by Professor Keon Jae Lee from the Department of Materials Science and Engineering at KAIST has developed in vivo silicon-based flexible large scale integrated circuits (LSI) for bio-medical wireless communication.
Silicon-based semiconductors have played significant roles in signal processing, nerve stimulation, memory storage, and wireless communication in implantable electronics. However, the rigid and bulky LSI chips have limited uses in in vivo devices due to incongruent contact with the curvilinear surfaces of human organs. Especially, artificial retinas recently approved by the Food and Drug Administration require extremely flexible and slim LSI to incorporate it within the cramped area of the human eye.
Although several research teams have fabricated flexible integrated circuits (ICs, tens of interconnected transistors) on plastics, their inaccurate nano-scale alignment on plastics has restricted the demonstration of flexible nano-transistors and their large scale interconnection for in vivo LSI applications such as main process unit (MPU), high density memory and wireless communication. Professor Lee's team previously demonstrated fully functional flexible memory using ultrathin silicon membranes (Nano Letters, Flexible Memristive Memory Array on Plastic Substrates), however, its integration level and transistor size (over micron scale) have limited functional applications for flexible consumer electronics.
Professor Keon Jae Lee's team fabricated radio frequency integrated circuits (RFICs) interconnected with thousand nano-transistors on silicon wafer by state-of-the-art CMOS process, and then they removed the entire bottom substrate except top 100 nm active circuit layer by wet chemical etching. The flexible RF switches for wireless communication were monolithically encapsulated with biocompatible liquid crystal polymers (LCPs) for in vivo bio-medical applications. Finally, they implanted the LCP encapsulated RFICs into live rats to demonstrate the stable operation of flexible devices under in vivo circumstances.
Professor Lee said, "This work could provide an approach to flexible LSI for an ideal artificial retina system and other bio-medical devices. Moreover, the result represents an exciting technology with the strong potential to realize fully flexible consumer electronics such as application processor (AP) for mobile operating system, high-capacity memory, and wireless communication in the near future."
This result was published in the May online issue of the American Chemical Society's journal ACS Nano. They are currently engaged in commercializing efforts of roll-to-roll printing of flexible LSI on large area plastic substrates.
Editor's Note:
A movie is available on YouTube showing the fabrication process for flexible LSI for flexible display, wearable computer and artificial retina for in vivo biomedical application: http://www.youtube.com/watch?v=5PpbM7m2PPs&feature=youtu.be
Disclaimer: This article is not intended to provide medical advice, diagnosis or treatment. Views expressed here do not necessarily reflect those of ScienceDaily or its staff.
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FILE - This Dec. 9, 2011 file photo shows an open tanning booth at Amazing Tans in Sacramento, Calif. The FDA announced Monday, May 6, 2013, it wants all tanning beds to carry language warning people under the age of 18 about the risks of indoor tanning. The agency would also require manufacturers to submit their beds for federal review before marketing them. (AP Photo/Rich Pedroncelli, File)
FILE - This Dec. 9, 2011 file photo shows an open tanning booth at Amazing Tans in Sacramento, Calif. The FDA announced Monday, May 6, 2013, it wants all tanning beds to carry language warning people under the age of 18 about the risks of indoor tanning. The agency would also require manufacturers to submit their beds for federal review before marketing them. (AP Photo/Rich Pedroncelli, File)
WASHINGTON (AP) ? Indoor tanning beds would carry new warnings about the risk of cancer and be subject to more stringent federal oversight, under a proposal unveiled Monday by the Food and Drug Administration.
The FDA wants all tanning beds to carry language warning people under the age of 18 about the risks of indoor tanning. The agency would also require manufacturers to meet certain safety and performance requirements before marketing their devices.
The government action is aimed at curbing cases of melanoma, the deadliest form of skin cancer, which have been on the rise for about 30 years. This year an estimated 76,690 people will be diagnosed with the disease, according to the American Cancer Society.
Recent studies have shown that the risk of melanoma is 75 percent higher in people who have been exposed to ultraviolet radiation from indoor tanning. While most cases are diagnosed in people in their 40s and 50s, the disease is linked to sun exposure at a young age.
Medical groups like the American Academy of Dermatology have been urging the U.S. government to take action on tanning beds for years, citing increases in the number of cases of skin cancer among women in their teens and twenties. Dermatologists say indoor tanning advertisements directly appeal to teenagers' desire to be attractive.
Currently the machines are classified as low-risk devices, in the same group as bandages and tongue depressors. By increasing their classification to moderate-risk, or class II, devices the FDA proposal could limit the levels of radiation the devices emit and make other changes to their design.
"The FDA's proposed changes will help address some of the risks associated with sunlamp products and provide consumers with clear and consistent information," FDA Commissioner Margaret Hamburg said in a statement.
The agency said it will take comments on its proposal for 90 days.
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This past weekend I had the pleasure of hosting a baby shower for our niece Natalie.? It's the first baby in the family since I had mine AND it's a girl so it was super fun to do something pink!!?
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It was a Big Fat Greek Baby Shower.? Natalie is a teacher, so I went with a little chalkboard and little pink & purple and lots of adorable baby shoes.?
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I made the Invitation, Thank You Notes, Dear Baby card and the food signs in My Digital Studio.
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The thank you note was 3 1/2 x 5 fold over card size.
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The shower was held at her mom's home (my sister in law)...we used the pool table for the food?and?sorry the lights were a little glaring for photographing.
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Center of the food table.
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Lots of yummy foods!. The best part of course! *?*
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Each centerpiece was a baby onsie with a tutu and matching shoes.? I put them on a jewelry stand and stuffed them with tissue to make a little tummy.?
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One of the activities was to make a baby headband.? I put them together in kits and everyone made a headband for the baby.? She ended up with about 25 darling headbands...that baby better LOVE headbands!? I made the elastics in different sizes so hopefully she will have plenty for a couple of years.
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One of her gifts was a nice chair from YiaYia...she will definitely need that!?
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Everyone filled this out for her and boy, was that fun to see the variety of names and well wishes for her baby.? This was a 5x7 single sided card.
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Not a great photo of the favors, but these are?miniature containers of baby wipes.
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Just 3" tall and about 2" wide with a keychain on them!? Adorable!!?
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Pop Up Posies FREE Tutorial
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Please order your Stampin' Up! supplies HERE.Source: http://inkingidaho.blogspot.com/2013/05/natalies-baby-shower.html
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FILE- In this Dec. 16, 2004 artist rendering released by the Lower Manhattan Development Corporation, the Memorial Hall looking at the South Footprint is shown. Faced with hefty operating costs, the foundation building the underground 9/11 museum at the World Trade Center has decided to charge a mandatory admission fee of $20 to $25 when the site opens in 2014. (AP Photo/Lower Manhattan Development Corp., File)
FILE- In this Dec. 16, 2004 artist rendering released by the Lower Manhattan Development Corporation, the Memorial Hall looking at the South Footprint is shown. Faced with hefty operating costs, the foundation building the underground 9/11 museum at the World Trade Center has decided to charge a mandatory admission fee of $20 to $25 when the site opens in 2014. (AP Photo/Lower Manhattan Development Corp., File)
FILE - In this Nov. 19, 2003 artist's rendering provided by the Lower Manhattan Development Corporation, a view of the reflecting pool from inside the National September 11 Museum and Memorial is shown. Faced with hefty operating costs, the foundation building the underground 9/11 museum at the World Trade Center has decided to charge a mandatory admission fee of $20 to $25 when the site opens in 2014. Memorial foundation head Joseph Daniels said Saturday, May 4, 2013, that the museum has little choice. (AP Photo/Lower Manhattan Development Corp., File)
A visitor to the Sept. 11 Memorial, left, poses for a photo as others, right, peer at the entrance line, Saturday, May 4, 2013, in New York. Faced with hefty operating costs, the foundation building the underground 9/11 museum at the World Trade Center has decided to charge a mandatory admission fee of $20 to $25 when the site opens next year. Entry to the memorial plaza with its twin reflecting pools will still be free, but the decision to charge for the underground museum housing relics of the terror attacks has been greeted with dismay by some relatives of trade center victims. (AP Photo/Mary Altaffer)
NEW YORK (AP) ? Faced with hefty operating costs, the foundation building the 9/11 museum at the World Trade Center has decided to charge an admission fee of $20 to $25 when the site opens next year.
The exact cost of the mandatory fee has not yet been decided.
Entry to the memorial plaza with its twin reflecting pools will still be free.
The decision to charge for the underground museum housing relics of the Sept. 11, 2001, terror attacks has been greeted with dismay by some relatives of 9/11 victims.
"People are coming to pay their respects and for different reasons," said Janice Testa of Valley Stream, whose firefighter brother Henry Miller Jr. died at the twin towers. "It shouldn't be a place where you go and see works of art. It should more be like a memorial place like a church that there's no entry fee."
Testa was visiting the memorial Saturday with relatives from Florida.
The memorial plaza opened in 2011 on the 10th anniversary of the terror attacks, but disputes over funding have pushed the museum's opening back to spring of 2014.
With the cost of operating the memorial and museum projected to be $60 million a year, the memorial foundation voted at its board meeting last week to charge a mandatory admission fee for the museum.
"This is something that is going to be important and is going to be worth the expenditure," Joseph Daniels, president of the National September 11 Memorial and Museum, said Saturday.
Daniels said the museum will be free during certain hours every week and will offer student and senior discounts.
Foundation officials had considered an optional donation but rejected the idea.
"We decided that it's more fiscally prudent to have a straight ticket charge," Daniels said.
Debra Burlingame, a foundation board member whose brother was the pilot of one of the hijacked planes, said the trade center site is expensive to build on and to protect.
"The World Trade Center site remains a target of interest among terrorists, so the security has to be robust and relentless," Burlingame said in a phone interview. "There's a big price tag on that.
"Would we like to be able to say this is free? Absolutely," Burlingame added. But she called it "irresponsible to hope that year after year we have donations that will cover an expense like security."
Some visitors to the memorial were divided about charging admission to the museum.
Retired school psychologist Valerie Cericola of Lavalette, N.J., said the entry fee sounded fair.
"You need to keep it open, you need to keep it running," she said. "It's an expense.
But Jennifer Reyes, a friend of Cericola's daughter who has a connection to the trade center site because she was born on Sept. 11, 2001, said the museum should ask for an optional donation.
"I think a donation like $10 would be good," Jennifer said.
___
AP radio correspondent Julie Walker contributed to this report.
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LOS ANGELES (AP) ? Charlie Sheen supports a decision by child protective services to remove his twin sons from the custody of his ex-wife and have them live temporarily with another of his exes, actress Denise Richards, his spokesman said Friday.
Larry Solters wrote in a statement that Sheen will participate in court proceedings related to ex-wife Brooke Mueller's custody of their 4-year-old sons. Mueller and Sheen were married in 2008 and divorced in 2011.
"He knows Max and Bob are safe and in a stable, loving environment with Denise and the boys' sisters," Solters wrote. "Charlie will fully cooperate and fully participate in all proceedings."
Celebrity website RadarOnline.com reported Friday that the twins were removed from Mueller's custody by the Department of Children and Family Services.
Mueller has struggled with addiction for years, but it remains unclear what prompted officials to remove her sons from her care. The agency's investigations are confidential, and Mueller and Richards' representatives have declined to comment.
Sheen and Richards have two daughters from their marriage, which ended in 2006.
Source: http://news.yahoo.com/sheen-supports-sons-removal-ex-wifes-care-001915309.html
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BY:
Longtime Obamacare advocate Sen. Chuck Schumer (D., N.Y.) acknowledged Wednesday that health care costs could ?go through the roof? in part because of that legislation during an interview with WHEC NBC Rochester:
SCHUMER: Our insurance department is empowered to protect families and we?re going to watch them like a hawk to make sure they do, because if they don?t, these rates could go through the roof ? It?s in part because of Obamacare, but health care costs have been going up in double digits for years and years and years. The good news is in this bill, there?s a way to stop it.
The remarks stand in contrast to talking points?emphasizing cost reduction employed by Schumer and other Democrats in defense of the Affordable Care Act.
Monday, Health and Human Services Secretary Kathleen Sebelius said she had not anticipated how complicated implementation of Obama?s legislation would be. This came on the heels of her March remarks that some purchasing new policies for themselves this fall could face higher premiums because of Obamacare requirements.
Source: http://freebeacon.com/schumer-health-insurance-rates-could-go-the-through-roof-because-of-obamacare/
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By Dan Williams
LOD, Israel (Reuters) - The dilemma Israel faces in trying to formulate a strategy on Syria two years into its civil war is symbolized by a case being heard in a small courtroom near Tel Aviv.
The state is prosecuting an Arab Israeli who briefly joined the rebel forces fighting to topple President Bashar al-Assad.
Arrested after his return to Israel, Hikmat Massarwa, a 29-year-old baker, is accused of unlawful military training, having contacts with foreign agents and traveling to a hostile state.
The trial hinges on the unanswered question of who, if anyone, Israel favors in the war and if the rebels will turn out to be friends or enemies.
The prosecutor in Lod is trying to depict Massarwa as having aligned himself with foes of Israel, but Judge Avraham Yaakov is struggling for clarity. "There's no legal guidance regarding the rebel groups fighting in Syria," he told a recent hearing.
Matters were simpler during the decades of unchallenged Assad family rule.
Technically Israeli is at war with its northern neighbor. It captured the Golan Heights in the 1967 Middle East War, built settlements and annexed the land. But belligerence was rare and the borderland has remained largely quiet for decades.
Assad's Syria is part of the so-called Axis of Resistance along with Iran and Lebanon's Hezbollah, both arch enemies of the Jewish state. But Syria itself avoided open conflict.
Israel was slow to welcome the uprising against Assad when it broke out in March 2011. Though some leaders now call for his overthrow, planners fret about what might follow.
"The question for us is no longer whether it is good or not if Assad stays in power, but how do we control our interests in this divided, murky situation which could last for decades," said Ofer Shelah of the Yesh Atid party, which is part of the government coalition.
The dilemma has grown more acute since Islamist fighters linked to al-Qaeda assumed a prominent role in the rebels' battle plans.
Israelis believe one in 10 of the rebels is a jihadi who might turn his gun on them once Assad is gone. They also worry that Hezbollah guerrillas allied to Assad could get hold of his chemical arsenal and other advanced weaponry.
So Israel has acted with restraint on Syria - shooting at its troops across the occupied Golan Heights only when hit by stray fire and playing down an Israeli airstrike on a suspected Hezbollah-bound convoy in January.
Officials say Israel has also been cool to Western proposals to increase aid to the Syrian rebels to help them match Assad's superior armed forces.
One Israeli official told Reuters that he responds to any suggestions of a foreign military role with the question: "Do you really know on whose behalf you'll be intervening?"
MIXED MESSAGES
But with Prime Minister Benjamin Netanyahu presiding over a new, right-leaning coalition and the Israeli military stretched by keeping vigil over several fronts - including Islamist-ruled Egypt - the message has been far from uniform.
Netanyahu may have contributed to this by framing Iran and its nuclear program as Israel's overriding regional concern, bolstering the case for removing Tehran's ally Assad.
When an Israeli intelligence analyst said last week that Assad's forces had used chemical weapons, both the Netanyahu government and its foreign allies were blindsided, according to officials.
Washington confirmed the Israeli assessment, thus posing a problem for U.S. President Barack Obama, who had said use of chemical arms would be a "red line".
Israel's deputy foreign minister urged U.S. action in Syria - a call slapped down by more senior figures.
Israel's ambassador to Washington, Michael Oren, said it was not making any policy recommendations to Obama on Syria.
"We think this issue is very complex," he told Reuters.
Several officials said Israel would be unlikely to attack Syria unilaterally unless it had evidence that chemical weapons had been handed over to Hezbollah.
Lacking enough of the specialized ground troops that would be needed for a search-and-destroy sweep of chemical weapons, Israel would probably have to rely on aerial bombing.
The Netanyhau government might even acquiesce if the rebels acquire the chemical weapons, on the assumption that the insurgents were mainstream Syrians keen to rebuild their country and loath to invite catastrophic war with Israel.
"If the jihadis get the chemical weapons, that's very bad, but there's still the hope that these people lack the hard-core military wherewithal, and required technical support in Syria, that would be required to use them," one Israeli official said.
Indeed, Israeli planners are debating to what extent the radical Sunni Islamists fighting Assad could eventually constitute a direct threat to Israel.
The chief military spokesman, Brigadier-General Yoav Mordechai, sounded the alarm last month by saying the "Global Jihad" - meaning al Qaeda and its affiliates - wielded the most clout on the Syrian-held side of the Golan Heights.
Other Israeli authorities are more optimistic. The Mossad intelligence agency estimates that Syria's entrenched secularism will dilute enmity to Israel, according to one official.
"The Islamists there aren't all Salafists, and the Salafists aren't all al Qaeda, by any means," the official said.
"We may not make peace, but I think we might find some kind of dialogue, if only for the sake of mutual deterrence."
Israel has given no indication that it already has contacts with Syria's opposition. But it has coordinated closely on security with Jordan, a supporter of some rebel factions.
Back in Judge Yaakov's courtroom, the fate of Massarwa, who faces a maximum of 15 years in jail if convicted, rests on whether the state can prove there is danger to Israel from the Free Syrian Army unit he stayed with for a week in March.
Massarwa's lawyer, Helal Jaber, hopes the logic of "my enemy's enemy is my friend" will win clemency for his client, who went to Syria via Turkey in search of a missing brother who had separately joined the rebels.
"The greatest democracies in the world, including the United States, are supporting the opposition to Assad," Jaber said. "So how can Israel fault someone for doing the same?"
(Additional reporting by Warren Strobel in Washington and Crispian Balmer in Jerusalem; Editing by Angus MacSwan)
Source: http://news.yahoo.com/taking-sides-syria-hard-choice-israel-112808311.html
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WASHINGTON (AP) ? Internet shoppers are moving closer to paying sales taxes for their online purchases. But the fight is far from over.
The Senate voted 63-30 Thursday to advance a bill that would impose state and local sales taxes on purchases made over the Internet. An agreement among senators delayed the Senate's final vote on passage until May 6, when senators return from a weeklong vacation.
Opponents hope senators hear from angry constituents over the next week, but they acknowledged they have a steep hill to climb to defeat the bill in the Senate.
Their best hope for stopping the bill may be in the House, where some Republicans consider it a tax increase. President Barack Obama supports the bill.
The bill would empower states to reach outside their borders and compel online retailers to collect state and local sales taxes for purchases made over the Internet. Under the bill, the sales taxes would be sent to the states where a shopper lives.
Under current law, states can only require stores to collect sales taxes if the store has a physical presence in the state. As a result, many online sales are essentially tax-free, giving Internet retailers an advantage over brick-and-mortar stores.
"We look forward to passing this landmark bill in 11 days and call on the House to stand up for America's Main Street businesses with us," Sen. Dick Durbin, D-Ill., said shortly after Thursday's vote.
Senate Democratic leaders wanted to finish work on the bill this week, before leaving town for the recess. But they were blocked by a handful of senators from states without sales taxes.
Oregon, Montana, New Hampshire and Delaware have no sales taxes, though the two senators from Delaware support the bill.
"I think it's going to be interesting for senators to get a response from constituents over this upcoming week," said Sen. Ron Wyden, D-Ore. "I'm not sure that the country knows that something like this coerces businesses all around America to collect other people's sales taxes."
The bill pits brick-and-mortar stores like Wal-Mart against online services such as eBay. The National Retail Federation supports it. And Amazon.com, which initially fought efforts in some states to make it collect sales taxes, supports it, too.
Retailers who have lobbied in favor of the bill celebrated Thursday's vote.
"The special treatment of big online businesses at the expense of retailers on Main Street will soon be a thing of the past," said Bill Hughes of the Retail Industry Leaders Association. "The overwhelmingly bipartisan support for leveling the playing field is rare in today's political environment and paves the way for a level playing field once and for all."
Supporters say the bill is about fairness for local businesses that already collect sales taxes, and lost revenue for states. Opponents say the bill would impose complicated regulations on retailers and doesn't have enough protections for small businesses. Businesses with less than $1 million a year in online sales would be exempt.
Many of the nation's governors ? Republicans and Democrats ? have been lobbying the federal government for years for the authority to collect sales taxes from online sales.
The issue is getting bigger for states as more people make purchases online. Last year, Internet sales in the U.S. totaled $226 billion, up nearly 16 percent from the previous year, according to Commerce Department estimates.
The National Conference of State Legislatures estimates that states lost $23 billion last year because they couldn't collect taxes on out-of-state sales.
Anti-tax groups have labeled the bill a tax increase. But it gets support from many Republicans who have pledged not to increase taxes. The bill's main sponsor is Sen. Mike Enzi, a conservative Republican from Wyoming. He has worked closely with Durbin, a liberal Democrat.
Enzi and Durbin say the bill doesn't raise taxes. Instead, they say, it gives states a mechanism to enforce current taxes.
In many states, shoppers are required to pay unpaid sales taxes when they file state tax returns. But governors complain that few people comply.
Under the bill, states that want to collect online sales taxes must provide free computer software to help retailers calculate the taxes, based on where shoppers live. States must also establish a single entity to receive Internet sales tax revenue, so retailers don't have to send them to individual counties or cities.
___
Follow Stephen Ohlemacher on Twitter: http://twitter.com/stephenatap
Source: http://news.yahoo.com/tax-free-internet-shopping-jeopardy-080503627--politics.html
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The Apogee Duet for iPad & Mac audio interface ($595 direct) brings stellar recording and playback capability to your iPad, iPhone, or Mac. Unlike the previous Duet 2, the new Duet has built-in iPad compatibility, which required some internal hardware changes. Granted, our Editors' Choice, the Focusrite iTrack Solo, which does the same thing, is much less expensive. But the Duet for iPad & Mac gives you your money's worth, thanks to its beautifully detailed audio quality, software integration, and ease of operation; you almost can't put a price tag on this level of performance.
Design and iPad Integration
I've already outlined the details in my review of the nearly identical Duet 2. Hit that review for a basic overview. Here, though, I'll focus on what makes the Apogee Duet for iPad & Mac different?and it's more than it appears, considering that the all-aluminum and glass enclosure, front panel, OLED display, and controls are exactly the same.
The iOS device integration is noteworthy in that it's a direct digital connection certified by Apple, without the need for the Camera Connection Kit, which only works with iPads, not iPhones or iPod touches. When connected, the Duet also charges iOS devices (although you'll need to plug in the bundled AC adapter), and offers iPad software control with Maestro, the company's low-latency mixer that works the same way on both iPads and Macs. In the hardware, iPad certification requires certain chips inside the peripheral device; it's more than just a firmware change, which is why existing Duet 2 owners can't add iPad connectivity without buying a whole new unit.
The Duet for iPad and Mac comes bundled with a cable loom with combination XLR and 1/4-inch instrument inputs and a pair of stereo 1/4-inch outputs, a usefully long 8-foot USB cable, an AC adapter, and an iPad cable. Unfortunately, the bundled iPad cable out of the box only works with older iPads, iPhones, and iPod touch devices with 30-pin connectors, not the newer Lightning Connector-equipped models; you'll need to pick up Apple's $29 Lightning-to-30-pin Adapter, which you can get at any Apple Store or online.
For this review, I tested the Apogee Duet for iPad & Mac with a 1st-generation Apple iPad, an Apple MacBook Pro 15-inch running OS X 10.8.2 (Mountain Lion), and a quad-core Xeon-based Mac Pro running OS X 10.7.5 (Lion), with a variety of programs including Avid Pro Tools 10 on the Mac and Apple GarageBand on the iPad.
Performance and Conclusions
Because the instrument and XLR cables are combined, you can't, say, leave a pair of stereo microphones connected while plugging in a guitar, the way you can with the Focusrite Forte. You also need the Duet's cable loom attached when driving a pair of studio monitor speakers, since the outputs aren't built into the enclosure like on the Forte.
That said, I'd rather have all of this than the Forte's key limitation, which is that you need the AC adapter plugged in whenever you're recording with phantom power, or whenever you need more headroom out of the headphone amp; the Duet doesn't have those limitations, and is much more of a portable audio interface for remote recording as a result, since you can run it from a MacBook Pro or MacBook Air's USB port.
The built-in mic preamps offer 75dB of gain range; Apogee says the company optimizes the mic pre circuit at each stepped gain setting to capture more dynamics and frequency bandwidth. Just as with the Duet 2, the Duet for iPad & Mac sounds incredible, during both playback and recording. Apogee makes a big point of the Duet's exceptional total harmonic distortion (THD) and noise floor figures, which mean a lot more here than they do in, say, the consumer electronics world, where stereo equipment manufacturers have been known to play with those numbers rather liberally.
In the real world, if you listen carefully, you can really hear the difference between the Duet and other interfaces?even against a direct competitor like the Focusrite Forte. The Forte sounds great, mind you; it records and plays back clean, pristine audio. But with the Duet, you get another level of midrange and high-end detail, both through the mic preamps, when tested with a Rode NT-1A large diaphragm condenser mic, and during playback, where you pick up a little more stereo separation and detail on individual instruments. You can make, mix, and monitor excellent recordings on either interface, but the Duet sounds just a bit better overall, in a variety of situations.
Recording on the iPad was also as easy as I expected; I installed the free Apogee Maestro app, which offers a similar interface to the desktop version. I plugged in the same mic, made sure phantom power was enabled, dialed in an appropriate level of gain, and recorded audio with GarageBand on top of MIDI virtual instrument tracks without a problem. Reliability was also rock solid throughout, on both test machines. I ran into some trouble with the earlier Duet 2, which may have been indicative of something up with my test systems, but the Duet for iPad & Mac ran flawlessly during the review?mimicking the behavior of the original FireWire-based Duet.
At the moment, the Apogee Duet for iPad & Mac is the best recording interface you can buy for the iPad. As far as computer recording is concerned, it's a little less clear, thanks to the host of competitors that have rushed to the scene since the original Apogee Duet proved a success following its launch in 2008. The Forte is an obvious choice if you're recording on the PC platform, thanks to its Windows compatibility, and it sounds really good in its own right, if slightly different than the Apogee Duet. Propellerhead Reason fans should have a look at the Propellerhead Balance, which offers clean sound and tight integration with Reason. Finally, if you're on a strict budget, you'll do well with the Editors' Choice Focusrite iTrack Solo which brings clear recording to PCs, Macs, and iPads at a low price, even if it lacks the level of detail and transparency that both the Duet and Forte offer.
Source: http://feedproxy.google.com/~r/ziffdavis/pcmag/~3/SUUt1-gFT40/0,2817,2417989,00.asp
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(Forimmediaterelease.net) YARDLEY, Pennsylvania - The results are in! For the first time, GlobalThe readers of Global Traveler are intrepid business travelers, but, according to the magazine?s most recent MediaMark Research survey, they are also frequent leisure travelers, averaging three international and six domestic leisure trips per year.
The awards were announced April 15, in the magazine?s first-ever Leisure Lifestyle Book, a special edition to Global Traveler?s monthly issue. The book also includes articles on 5-star, all-inclusive resorts, signature cocktails, restaurant and hotel rankings, indigenous spa treatments, and butler service.
This year's roster of inaugural winners includes Turkey (Best Historical Attractions), New Zealand (Best Hiking Destination), Silversea Cruises (Best Small Ship Cruise Line), InterContinental Resort&Thalasso Spa, Bora Bora (Best Resort in Asia and the Pacific), Hilton Seychelles Labriz Resort&Spa (Best Resort in Africa), Kaua?i (Best Island in the United States and Canada) and Capri (Best Island in Europe).
?We are excited to announce the first annual Leisure Travel Awards, in conjunction with our new Leisure Lifestyle Book,? said Francis X. Gallagher, publisher and CEO of Global Traveler. ?Our readers are traveling all the time ? for business and pleasure. Nearly all we do recognizes the business travel segment, and we realized it is important to recognize, honor, and highlight leisure travel. Our knowledgeable readers are frequenting these winners ? the very best cruise lines, resorts, and destinations for leisure travel.?
A complete list of winners is as follows:
- est Spa: The Peninsula Bangkok
- Best Shopping: Hong Kong
- Best Natural Attractions: Australia
- Best Historical Attractions: Turkey
- Best Skiing: Switzerland
- Best Beach Destination: British Virgin Islands
- Best Adventure Travel Destination: Australia
- Best Safari Destination: South Africa
- Best Hiking Destination: New Zealand
- Best Small Ship Cruise Line: Silversea Cruises
- Best Large Ship Cruise Line: Celebrity Cruises
- Best River Cruise Line: Viking River Cruises
- Best Resort in the United States and Canada: The Phoenician
- Best Resort in Hawaii: Hilton Hawaiian Village&Waikiki Beach Resort
- Best Resort in the Caribbean: Four Seasons Resort Nevis
- Best Resort in South America: The Ritz-Carlton, Santiago
- Best Resort in Mexico: Hilton Los Cabos Beach&Golf Resort
- Best Resort in Asia and the Pacific: InterContinental Resort&Thalasso Spa,
Bora Bora
- Best Resort in Europe: The St. Regis Mardavall Mallorca Resort
- Best Resort in Africa: Hilton Seychelles Labriz Resort&Spa
- Best Resort in the Middle East: Emirates Palace
- Best Luxury Tour Operator: Abercrombie&Kent
- Best Island in the United States and Canada: Kaua?i, Hawai?i
- Best Island in the Caribbean: Saint Lucia
- Best Island in Mexico and Central/South America: Galapagos
- Best Island in Australia and the South Pacific: Bora Bora
- Best Island in Europe: Capri
- Best Island in Asia and Africa: Bali
ABOUT GLOBAL TRAVELER/FXEXPRESS PUBLICATIONS, INC.
Global Traveler, the only ABC-audited U.S.-based magazine for the international
business traveler, is a business travel and lifestyle publication with an ABC paid circulation of 107,140+. FXExpress Publications, Inc., based in Yardley, Pennsylvania, is a privately-held company publishing Global Traveler, eFlyer USA; eFlyer Asia and several annuals; and also operating www.globaltravelerusa.com , www.globaltravellerasia.com
and www.globaltravelerusa.com/blog .
MEDIA CONTACT: Kimberly Krol, tel 267 364 5811, ext. 202, kim.krol@globaltravelerusa.com
Source: http://www.forimmediaterelease.net/pm/8722.html
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